TYSY Antibody (C-term)

APR07199G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07199G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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TYSY Antibody (C-term)

品牌	Leading Biology	貨號	APR07199G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TYSY antibody (C-term).
分子量	35716 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	265-294 aa
靶點	This TYSY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
亞型	Rabbit Ig
通用名	TS
基因ID	7298
UniProt ID	P04818
功能	Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
總結(jié)	Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, IF, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 IF~~1:10~50
別名	Thymidylate synthase, TS, TSase, TYMS, TS
圖像	Western blot analysis of lysate from Jurkat cell line, using TYSY Antibody (C-term)( APR07199G). APR07199G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. Western blot analysis of lysates from Jurkat, HL-60 cell line (from left to right), using TYSY Antibody (C-term)( APR07199G). APR07199G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. Formalin-fixed and paraffin-embedded human colon carcinoma with TYSY Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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