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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > SFN Antibody (C-term)

SFN Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
APR13300G 100 μl / ¥4950

SFN Antibody (C-term)

品牌

Leading Biology

貨號

APR13300G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFN antibody (C-term).

分子量

27774 Da

細胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

222-248 aa

靶點

This SFN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of human SFN.

亞型

Rabbit Ig

通用名

HME1

基因ID

UniProt ID

功能

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, FC, E

稀釋方法

WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50 FC~~1:10~50

別名

14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1

圖像

Western blot analysis of lysates from A431, Hela cell line (from left to right), using SFN Antibody (C-term) ( APR13300G). APR13300G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

SFN antibody (C-term) (Cat. APR13300G) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SFN antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of SFN Antibody (C-term)(Cat. APR13300G) with A549 cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

說明書

數(shù)量

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