CYK18 Antibody (C-term)

APR15653G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15653G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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CYK18 Antibody (C-term)

品牌	Leading Biology	貨號	APR15653G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYK18 antibody (C-term).
分子量	48058 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, perinuclear region. Nucleus, nucleolus
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	401-430 aa
靶點	This CYK18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human CYK18.
克隆號	RB18746
亞型	Rabbit Ig
通用名	CYK18
基因ID	3875
UniProt ID	P05783
功能	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
總結(jié)	KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	FC, IHC-P, IF, WB, E
稀釋方法	WB~~1:2000 IHC-P~~1:1000 FC~~1:50 IF~~1:200
別名	Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
圖像	CYK18 Antibody (C-term) (Cat. APR15653G) western blot analysis in WiDr,MDA-MB231,Hela,ZR-75-1,K562,NCI-H460,NCI-H292,HepG2 cell line lysates (35ug/lane).This demonstrates the CYK18 antibody detected the CYK18 protein (arrow). CYK18 Antibody (C-term)(Cat. APR15653G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYK18 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. CYK18 Antibody (C-term) (Cat. APR15653G)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung adenocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYK18 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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