CROT Antibody (N-term)

APG02771G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APG02771G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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CROT Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APG02771G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CROT antibody (N-term).
分子量	70178 Da
細(xì)胞定位	Antigen Cellular Localization: Peroxisome.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	49-79 aa
靶點(diǎn)	This CROT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of human CROT.
亞型	Rabbit Ig
通用名	COT
基因ID	54677
UniProt ID	Q9UKG9
功能	Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl- CoA, to its corresponding carnitine ester.
總結(jié)	CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	FC, IHC-P, WB, E
稀釋方法	FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000
別名	Peroxisomal carnitine O-octanoyltransferase, COT, CROT, COT
圖像	CROT Antibody (N-term)(Cat. APG02771G) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human brain tissue reacted with CROT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of CROT Antibody (N-term) (Cat. APG02771G) in K562 cell line and mouse liver tissue lysates (35ug/lane). CROT (arrow) was detected using the purified Pab.
說(shuō)明書(shū)	Product Datasheet Protocol
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