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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Fructose 6 Phosphate Kinase (PFKM) Antibody (C-term)

Fructose 6 Phosphate Kinase (PFKM) Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
AMM04615G 100 μl / ¥4950

Fructose 6 Phosphate Kinase (PFKM) Antibody (C-term)

品牌

Leading Biology

貨號

AMM04615G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Fructose 6 Phosphate Kinase (PFKM) antibody (C-term).

分子量

85183 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

746-776 aa

靶點(diǎn)

This Fructose 6 Phosphate Kinase (PFKM) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 746-776 amino acids from the C-terminal region of human Fructose 6 Phosphate Kinase (PFKM).

亞型

Rabbit Ig

通用名

PFKX

基因ID

UniProt ID

功能

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.

總結(jié)

Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

稀釋方法

WB~~1:1000 IHC-P~~1:50~100 IF~~1:10~50

別名

ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255|HAMAP-Rule:MF_03184}, ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}, PFK-M, 27111 {ECO:0000255|HAMAP-Rule:MF_03184}, 6-phosphofructokinase type A, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184}, PFKM, PFKX

圖像

Western blot analysis of PFKM polyclonal antibody (Cat. AMM04615G) in Hela cell line lysate. PFKM(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PFKM Antibody (C-term)(Cat. AMM04615G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKM antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

說明書

數(shù)量

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