HS2ST1 Antibody (N-term)

APR16720G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR16720G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HS2ST1 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR16720G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HS2ST1 antibody (N-term).
分子量	41881 Da
細(xì)胞定位	Antigen Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	16-45 aa
靶點(diǎn)	This HS2ST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human HS2ST1.
亞型	Rabbit Ig
通用名	HS2ST, KIAA0448
基因ID	9653
UniProt ID	Q7LGA3
功能	Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity).
總結(jié)	Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Heparan sulfate 2-O-sulfotransferase is a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of the HS2ST1 gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Heparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST, 282-, HS2ST1, HS2ST, KIAA0448
圖像	Western blot analysis of HS2ST1 (arrow) using rabbit polyclonal HS2ST1 Antibody (N-term) ( APR16720G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HS2ST1 gene (Lane 2) (Origene Technologies). Western blot analysis of HS2ST1 Antibody (N-term) ( APR16720G) in HL-60 cell line lysates (35ug/lane).HS2ST1 (arrow) was detected using the purified Pab.
說(shuō)明書(shū)	Product Datasheet Protocol
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