品牌 |
Leading Biology | 貨號(hào) |
APR10110G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC47A1 antibody (C-term).
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分子量 |
61922 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Note=Predominantly localized at the plasma membrane but also found in intracellular organelles
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
492-519 aa
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靶點(diǎn) |
This SLC47A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-519 amino acids from the C-terminal region of human SLC47A1.
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亞型 |
Rabbit Ig
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通用名 |
MATE1
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基因ID |
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UniProt ID |
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功能 |
Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
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總結(jié) |
SLC47A1 is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Multidrug and toxin extrusion protein 1, MATE-1, hMATE-1, Solute carrier family 47 member 1, SLC47A1, MATE1
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圖像 |
SLC47A1 Antibody (C-term) (Cat. APR10110G) western blot analysis in HepG2(lane 1),MDA-MB435(lane 2) cell line lysates (35ug/lane).This demonstrates the SLC47A1 antibody detected the SLC47A1 protein (arrow). SLC47A1 Antibody (C-term) (Cat. APR10110G) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC47A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書(shū) |
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數(shù)量 |
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