全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR09154G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-beclin 1(S64) antibody.
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分子量 |
51896 Da
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細胞定位 |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
This beclin 1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S64 of human beclin 1.
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亞型 |
Rabbit Ig
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通用名 |
GT197
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基因ID |
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UniProt ID |
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功能 |
Plays a central role in autophagy (PubMed:23184933). Required for the abcission step in cytokinesis (PubMed:20208530). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
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總結(jié) |
Beclin-1 participates in the regulation of autophagy andhas an important role in development, tumorigenesis, andneurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[suppliedby OMIM].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
DB, E
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稀釋方法 |
DB~~1:500
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別名 |
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
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圖像 |
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說明書 |
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數(shù)量 |
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