ZIC3 Antibody (Center)

APR14040G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14040G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ZIC3 Antibody (Center)

品牌	Leading Biology	貨號	APR14040G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZIC3 antibody (Center).
分子量	50569 Da
細胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.
宿主	Rabbit
種屬反應性	Human
免疫原	239-267 aa
靶點	This ZIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human ZIC3.
亞型	Rabbit Ig
通用名	ZNF203
基因ID	7547
UniProt ID	O60481
功能	Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
總結(jié)	This gene encodes a member of the ZIC family of C2H2-typezinc finger proteins. This nuclear protein probably functions as atranscription factor in early stages of left-right body axisformation. Mutations in this gene cause X-linked visceralheterotaxy, which includes congenital heart disease and left-rightaxis defects in organs.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203
圖像	Anti-ZIC3 Antibody (Center) at 1:1000 dilution + HL-60 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST. ZIC3 Antibody (Center) (Cat. APR14040G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ZIC3 antibody detected the ZIC3 protein (arrow). ZIC3 Antibody (Center) (Cat. APR14040G) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZIC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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