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CYP26A1 Antibody (C-term)

APG02876G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG02876G		100 μl / ￥4950

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CYP26A1 Antibody (C-term)

品牌	Leading Biology	貨號	APG02876G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP26A1 antibody (C-term).
分子量	56199 Da
細胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
宿主	Rabbit
種屬反應性	Human, Mouse
免疫原	467-497 aa
靶點	This CYP26A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-497 amino acids from the C-terminal region of human CYP26A1.
亞型	Rabbit Ig
通用名	CYP26, P450RAI1
基因ID	1592
UniProt ID	O43174
功能	Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
總結	CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Cytochrome P450 26A1, 114--, Cytochrome P450 retinoic acid-inactivating 1, Cytochrome P450RAI, hP450RAI, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome, CYP26A1, CYP26, P450RAI1
圖像	Western blot analysis of CYP26A1 Antibody (C-term) (Cat. APG02876G) in mouse NIH-3T3 cell lysates (35ug/lane).CYP26A1 (arrow) was detected using the purified Pab. CYP26A1 Antibody (C-term)(Cat. APG02876G) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CYP26A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. CYP26A1 Antibody (C-term) (Cat. APG02876G) flow cytometric analysis of NIH-3T3 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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