S adenosylhomocysteine hydrolase (ACHY) Antibody (C-term)

AMR09797G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMR09797G		100 μl / ￥4950

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S adenosylhomocysteine hydrolase (ACHY) Antibody (C-term)

品牌	Leading Biology	貨號	AMR09797G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S adenosylhomocysteine hydrolase (ACHY) antibody (C-term).
分子量	47716 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
宿主	Rabbit
種屬反應性	Human
免疫原	407-432 aa
靶點	This S adenosylhomocysteine hydrolase (ACHY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-432 amino acids from the C-terminal region of human S adenosylhomocysteine hydrolase (ACHY).
亞型	Rabbit Ig
通用名	SAHH
基因ID	191
UniProt ID	P23526
功能	Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
總結	S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, AHCY, SAHH
圖像	Western blot analysis of anti-AHCY Antibody (C-term)(Cat. AMR09797G) in HepG2 cell line lysates (35ug/lane). AHCY(arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AHCY antibody (C-term) (Cat. AMR09797G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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S adenosylhomocysteine hydrolase (ACHY) Antibody (C-term)