ZMPSTE24 Antibody (Center)

APR14303G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR14303G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ZMPSTE24 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR14303G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZMPSTE24 antibody (Center).
分子量	54813 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	400-430 aa
靶點(diǎn)	This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the Central region of human ZMPSTE24.
亞型	Rabbit Ig
通用名	FACE1, STE24
基因ID	10269
UniProt ID	O75844
功能	Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
總結(jié)	ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
別名	CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
圖像	All lanes : Anti-ZMPSTE24 Antibody (E415) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: human kidney lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST. The anti-ZMPSTE24 Pab (Cat. APR14303G) is used in Western blot to detect ZMPSTE24 in mouse cerebellum tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
說明書	Product Datasheet Protocol
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