(Mouse) Sox17 Antibody (C-term)

APR14742G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14742G		100 μl / ￥4950

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(Mouse) Sox17 Antibody (C-term)

品牌	Leading Biology	貨號	APR14742G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (Mouse) Sox17 antibody (C-term).
分子量	44646 Da
細胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00267, ECO:0000269\|PubMed:20802155}
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點	This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17.
亞型	Rabbit Ig
通用名	Sox-17
基因ID	20671
UniProt ID	Q61473
功能	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
總結(jié)	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Transcription factor SOX-17, Sox17, Sox-17
圖像	Western blot analysis of lysates from LNCaP, mouse F9 cell line (from left to right), using Sox17 Antibody (C-term)( APR14742G). APR14742G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
說明書	Product Datasheet Protocol
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