ITPA Antibody (C-term)

APR08048G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR08048G		100 μl / ￥4950

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ITPA Antibody (C-term)

品牌	Leading Biology	貨號	APR08048G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITPA antibody (C-term).
分子量	21446 Da
細胞定位	Antigen Cellular Localization: Cytoplasm {ECO:0000255\|HAMAP-Rule:MF_03148, ECO:0000269\|PubMed:11278832}
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	149-178 aa
靶點	This ITPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the C-terminal region of human ITPA.
亞型	Rabbit Ig
通用名	C20orf37
基因ID	3704
UniProt ID	Q9BY32
功能	Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
總結(jié)	The protein encoded by this gene hydrolyzes inosinetriphosphate and deoxyinosine triphosphate to the monophosphatenucleotide and diphosphate. The encoded protein, which is a memberof the HAM1 NTPase protein family, is found in the cytoplasm andacts as a homodimer. Defects in the encoded protein can result ininosine triphosphate pyrophosphorylase deficiency. Two transcriptvariants encoding two different isoforms have been found for thisgene. Also, at least two other transcript variants have beenidentified which are probably regulatory rather thanprotein-coding.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Inosine triphosphate pyrophosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, ITPase {ECO:0000255\|HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, 36119 {ECO:0000255\|HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}, NTPase {ECO:0000255\|HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255\|HAMAP-Rule:MF_03148}, C20orf37
圖像	ITPA Antibody (C-term) (Cat. APR08048G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ITPA antibody detected the ITPA protein (arrow).
說明書	Product Datasheet Protocol
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