GNRHR Antibody (N-term)

APS00032G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APS00032G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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GNRHR Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APS00032G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GNRHR antibody (N-term).
分子量	37731 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	49-77 aa
靶點(diǎn)	This GNRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GNRHR.
亞型	Rabbit Ig
通用名	GRHR
基因ID	2798
UniProt ID	P30968
功能	Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
總結(jié)	This gene encodes the receptor for type 1gonadotropin-releasing hormone. This receptor is a member of theseven-transmembrane, G-protein coupled receptor (GPCR) family. Itis expressed on the surface of pituitary gonadotrope cells as wellas lymphocytes, breast, ovary, and prostate. Following binding ofgonadotropin-releasing hormone, the receptor associates withG-proteins that activate a phosphatidylinositol-calcium secondmessenger system. Activation of the receptor ultimately causes therelease of gonadotropic luteinizing hormone (LH) and folliclestimulating hormone (FSH). Defects in this gene are a cause ofhypogonadotropic hypogonadism (HH). Alternative splicing results inmultiple transcript variants encoding different isoforms. More than18 transcription initiation sites in the 5' region and multiplepolyA signals in the 3' region have been identified for this gene.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R, GNRHR, GRHR
圖像	Western blot analysis of lysate from human ovary tissue lysate, using GNRHR Antibody (N-term)(Cat. APS00032G). APS00032G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
說(shuō)明書	Product Datasheet Protocol
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