品牌 |
Leading Biology | 貨號(hào) |
AMM08485G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VPS37C antibody (Center).
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分子量 |
38659 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Late endosome membrane; Peripheral membrane protein. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
142-169 aa
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靶點(diǎn) |
This VPS37C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VPS37C.
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亞型 |
Rabbit Ig
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通用名 |
PML39
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基因ID |
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UniProt ID |
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功能 |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
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總結(jié) |
VPS37C is a subunit of ESCRT-I (endosomal sorting complexrequired for transport I), a complex in the class E vacuolarprotein sorting (VPS) pathway required for sorting ubiquitinatedtransmembrane proteins into internal vesicles of multivesicularbodies (Eastman et al., 2005 [PubMed 15509564]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Vacuolar protein sorting-associated protein 37C, hVps37C, ESCRT-I complex subunit VPS37C, VPS37C, PML39
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圖像 |
VPS37C Antibody (Center) (Cat. AMM08485G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the VPS37C antibody detected the VPS37C protein (arrow). |
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說明書 |
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數(shù)量 |
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