全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17258G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LY96 antibody (C-term).
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分子量 |
18546 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
103-132 aa
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靶點(diǎn) |
This LY96 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human LY96.
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亞型 |
Rabbit Ig
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通用名 |
ESOP1, MD2
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基因ID |
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UniProt ID |
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功能 |
Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
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總結(jié) |
This gene encodes a protein which associates withtoll-like receptor 4 on the cell surface and confers responsivenessto lipopolysaccyaride (LPS), thus providing a link between thereceptor and LPS signaling. Studies of the mouse ortholog suggestthat this gene may be involved in endotoxin neutralization.Alternative splicing results in multiple transcript variantsencoding different isoforms.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2
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圖像 |
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說明書 |
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數(shù)量 |
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