TPP1 Antibody (N-term)

APR13781G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR13781G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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TPP1 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR13781G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TPP1 antibody (N-term).
分子量	61248 Da
細(xì)胞定位	Antigen Cellular Localization: Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	6-34 aa
靶點(diǎn)	This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.
亞型	Rabbit Ig
通用名	CLN2
基因ID	1200
UniProt ID	O14773
功能	Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity).
總結(jié)	This gene encodes a member of the sedolisin family ofserine proteases. The protease functions in the lysosome to cleaveN-terminal tripeptides from substrates, and has weakerendopeptidase activity. It is synthesized as acatalytically-inactive enzyme which is activated andauto-proteolyzed upon acidification. Mutations in this gene resultin late-infantile neuronal ceroid lipofuscinosis, which isassociated with the failure to degrade specific neuropeptides and asubunit of ATP synthase in the lysosome.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Tripeptidyl-peptidase 1, TPP-1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I, TPP1, CLN2
圖像	TPP1 Antibody (N-term) (Cat. APR13781G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TPP1 antibody detected the TPP1 protein (arrow).
說明書	Product Datasheet Protocol
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