MYH9 Antibody (N-term Y158)

APR17498G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR17498G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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MYH9 Antibody (N-term Y158)

品牌	Leading Biology	貨號(hào)	APR17498G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYH9 antibody (N-term Y158).
分子量	226532 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	134-165 aa
靶點(diǎn)	This MYH9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-165 amino acids from the N-terminal region of human MYH9.
亞型	Rabbit Ig
基因ID	4627
UniProt ID	P35579
功能	Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.
總結(jié)	This gene encodes a myosin IIA heavy chain that containsan IQ domain and a myosin head-like domain. The protein is involvedin several important functions, including cytokinesis, cellmotility and maintenance of cell shape. Defects in MYH9 are thecause of non-syndromic sensorineural deafness autosomal dominanttype 17, Epstein syndrome, Alport syndrome withmacrothrombocytopenia, Sebastian syndrome, Fechtner syndrome andmacrothrombocytopenia with progressive sensorineural deafness.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, FC, E
稀釋方法	WB~~1:1000 FC~~1:10~50
別名	Myosin-9, Cellular myosin heavy chain, type A, Myosin heavy chain 9, Myosin heavy chain, non-muscle IIa, Non-muscle myosin heavy chain A, NMMHC-A, Non-muscle myosin heavy chain IIa, NMMHC II-a, NMMHC-IIA, MYH9
圖像	All lanes : Anti-MYH9 Antibody (N-term Y158) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 227 kDa Blocking/Dilution buffer: 5% NFDM/TBST. MYH9 Antibody (N-term Y158) (Cat. APR17498G) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MYH9 antibody detected the MYH9 protein (arrow). MYH9 Antibody (N-term Y158) (Cat. APR17498G) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說(shuō)明書	Product Datasheet Protocol
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