品牌 |
Leading Biology | 貨號 |
APR12644G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2RX1 antibody (C-term).
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分子量 |
44980 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
345-372 aa
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靶點 |
This P2RX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.
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亞型 |
Rabbit Ig
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通用名 |
P2X1
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基因ID |
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UniProt ID |
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功能 |
Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
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總結 |
The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel with relatively high calcium permeability. Binding toATP mediates synaptic transmission between neurons and from neuronsto smooth muscle, being responsible, for example, for sympatheticvasoconstriction in small arteries, arterioles and vas deferens.Mouse studies suggest that this receptor is essential for normalmale reproductive function. It is possible that the development ofselective antagonists for this receptor may provide an effectivenon-hormonal male contraceptive pill.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1
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圖像 |
P2RX1 Antibody (C-term) (Cat. APR12644G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX1 antibody detected the P2RX1 protein (arrow). |
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說明書 |
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數(shù)量 |
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