全部產品分類
品牌 |
Leading Biology | 貨號 |
APR13242G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
|
產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEMA4A antibody (N-term).
|
||
分子量 |
83574 Da
|
||
細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
|
||
宿主 |
Rabbit
|
||
種屬反應性 |
Human, Mouse
|
||
免疫原 |
151-180 aa
|
||
靶點 |
This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A.
|
||
亞型 |
Rabbit Ig
|
||
通用名 |
SEMAB, SEMB
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity).
|
||
總結 |
This gene encodes a member of the semaphorin family ofsoluble and transmembrane proteins. Semaphorins are involved innumerous functions, including axon guidance, morphogenesis,carcinogenesis, and immunomodulation. The encoded protein is asingle-pass type I membrane protein containing animmunoglobulin-like C2-type domain, a PSI domain and a sema domain.It inhibits axonal extension by providing local signals to specifyterritories inaccessible for growing axons. It is an activator ofT-cell-mediated immunity and suppresses vascular endothelial growthfactor (VEGF)-mediated endothelial cell migration and proliferationin vitro and angiogenesis in vivo. Mutations in this gene areassociated with retinal degenerative diseases including retinitispigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10).Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified.
|
||
形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
|
||
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應用 |
WB, E
|
||
稀釋方法 |
WB~~1:1000
|
||
別名 |
Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB
|
||
圖像 |
|
||
說明書 |
|||
數量 |
|
||
| 選擇 | 品牌 | 貨號 | 產品名稱 | 規(guī)格 | 分類 | 研究領域 | 說明書 | 數量 | 目錄價 | |
| 1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 | ||
| 4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 | ||
| 6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 |
微信掃描二維碼，隨時隨地與小諾親密接觸，精彩活動，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)