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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > FNBP1L Antibody (Center)

FNBP1L Antibody (Center)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM05885G 100 μl / ¥4950

FNBP1L Antibody (Center)

品牌

Leading Biology

貨號(hào)

AMM05885G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FNBP1L antibody (Center).

分子量

70065 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse

免疫原

349-377 aa

靶點(diǎn)

This FNBP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human FNBP1L.

亞型

Rabbit Ig

通用名

C1orf39, TOCA1

基因ID

UniProt ID

功能

Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.

總結(jié)

The protein encoded by this gene binds to both CDC42 andN-WASP. This protein promotes CDC42-induced actin polymerization byactivating the N-WASP-WIP complex and, therefore, is involved in apathway that links cell surface signals to the actin cytoskeleton.Alternative splicing results in multiple transcript variantsencoding different isoforms.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Formin-binding protein 1-like, Transducer of Cdc42-dependent actin assembly protein 1, Toca-1, FNBP1L, C1orf39, TOCA1

圖像

FNBP1L Antibody (Center) (Cat. AMM05885G) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow).

說明書

數(shù)量

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