品牌 |
Leading Biology | 貨號(hào) |
APR17197G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LIMA1 antibody (N-term).
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分子量 |
85226 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=This cytoskeletal protein co- localizes with actin stress fibers and focal adhesion plaques
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
135-163 aa
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靶點(diǎn) |
This LIMA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the N-terminal region of human LIMA1.
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亞型 |
Rabbit Ig
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通用名 |
EPLIN, SREBP3
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基因ID |
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UniProt ID |
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功能 |
Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.
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總結(jié) |
EPLIN is a cytoskeleton-associated protein that inhibitsactin filament depolymerization and cross-links filaments inbundles (Maul et al., 2003 [PubMed 12566430]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
LIM domain and actin-binding protein 1, Epithelial protein lost in neoplasm, LIMA1, EPLIN, SREBP3
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圖像 |
LIMA1 Antibody (N-term) (Cat. APR17197G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow). |
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說(shuō)明書 |
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數(shù)量 |
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