全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR07604G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DNAJC24 antibody (Center).
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分子量 |
17008 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
53-81 aa
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靶點(diǎn) |
This DNAJC24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human DNAJC24.
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亞型 |
Rabbit Ig
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通用名 |
DPH4, ZCSL3
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基因ID |
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UniProt ID |
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功能 |
Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
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總結(jié) |
Diphthamide is a unique posttranslationally modifiedhistidine found only in translation elongation factor-2 (EEF2; MIM130610). This modification is conserved from archaebacteria tohumans and serves as the target for ADP-ribosylation andinactivation of EEF2 by diphtheria toxin (DT) and Pseudomonasexotoxin A. DPH4 is 1 of several enzymes involved in synthesis ofdiphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[suppliedby OMIM].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
DnaJ homolog subfamily C member 24, CSL-type zinc finger-containing protein 3, Diphthamide biosynthesis protein 4, DNAJC24, DPH4, ZCSL3
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圖像 |
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說明書 |
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數(shù)量 |
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