品牌 |
Leading Biology | 貨號(hào) |
APR13965G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VILIP3 antibody (N-term).
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分子量 |
22313 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
2-32 aa
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靶點(diǎn) |
This VILIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human VILIP3.
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亞型 |
Rabbit Ig
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通用名 |
BDR1
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基因ID |
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UniProt ID |
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功能 |
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
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總結(jié) |
VILIP3 is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. There are two alternatively spliced transcript variants of this gene, with multiple polyadenylation sites. Transcript variant 1 utilizes a different exon and also lacks one exon in the 5' UTR, as compared to variant 2; thus, the encoded protein is the same.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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別名 |
Hippocalcin-like protein 1, Calcium-binding protein BDR-1, HLP2, Visinin-like protein 3, VILIP-3, HPCAL1, BDR1
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圖像 |
Western blot analysis of VILIP3 (arrow) using rabbit polyclonal VILIP3 Antibody (N-term) (Cat. APR13965G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the VILIP3 gene (Lane 2) (Origene Technologies). The anti-VILIP3 Pab (Cat. APR13965G) is used in Western blot to detect VILIP3 in mouse cerebellum tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma |
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說(shuō)明書 |
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數(shù)量 |
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