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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Connexin 31 Antibody (C-term)

Connexin 31 Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
APR11633G 100 μl / ¥4950

Connexin 31 Antibody (C-term)

品牌

Leading Biology

貨號

APR11633G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Connexin 31 antibody (C-term).

分子量

30818 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

204-233 aa

靶點

This Connexin 31 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204~233 amino acids from the C-terminal region of human GJB3.

亞型

Rabbit Ig

通用名

CX31

基因ID

UniProt ID

功能

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

總結(jié)

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Gap junction beta-3 protein, Connexin-31, Cx31, GJB3, CX31

圖像

All lanes : Anti-GJB3 Antibody (C211) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

說明書

數(shù)量

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