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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Connexin 30.3 Antibody (N-term)

Connexin 30.3 Antibody (N-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR11266G 100 μl / ¥4950

Connexin 30.3 Antibody (N-term)

品牌

Leading Biology

貨號(hào)

APR11266G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Connexin 30.3 antibody (N-term).

分子量

30419 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

90-120 aa

靶點(diǎn)

This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

總結(jié)

Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Gap junction beta-4 protein, Connexin-303, Cx303, GJB4

圖像

Western blot analysis of GJB4 (arrow) using rabbit polyclonal GJB4 Antibody (H105.Connexin) (Cat. AP1544c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GJB4 gene.

說明書

數(shù)量

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