品牌 |
Leading Biology | 貨號(hào) |
AMM07311G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPP6C antibody (C-term).
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分子量 |
35144 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
264-293 aa
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靶點(diǎn) |
This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human PPP6C.
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亞型 |
Rabbit Ig
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通用名 |
PPP6
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基因ID |
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UniProt ID |
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功能 |
Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
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總結(jié) |
This gene encodes the catalytic subunit of proteinphosphatase, a component of a signaling pathway regulating cellcycle progression. Splice variants encoding different proteinisoforms exist. The pseudogene of this gene is located onchromosome X.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6
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圖像 |
Anti-PPP6C Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 35 kDa Blocking/Dilution buffer: 5% NFDM/TBST. PPP6C Antibody (C-term) (Cat. AMM07311G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PPP6C antibody detected the PPP6C protein (arrow). |
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說明書 |
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數(shù)量 |
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