ARC Antibody (N-term)

APR11458G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR11458G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ARC Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR11458G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARC antibody (N-term).
分子量	45316 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytoskeleton. Endosome {ECO:0000250\|UniProtKB:Q63053, ECO:0000250\|UniProtKB:Q9WV31}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250\|UniProtKB:Q63053, ECO:0000250\|UniProtKB:Q9WV31}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity). Enriched on the plasma membrane. {ECO:0000250, ECO:0000269\|PubMed:21834987}
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	37-66 aa
靶點(diǎn)	This ARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human ARC.
亞型	Rabbit Ig
基因ID	23237
UniProt ID	Q7LC44
功能	Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
總結(jié)	ARCis required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Activity-regulated cytoskeleton-associated protein, ARC/ARG31, Activity-regulated gene 31 protein homolog, Arg31, ARC {ECO:0000312\|EMBL:AAG337051}
圖像	ARC Antibody (N-term) (Cat. APR11458G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ARC antibody detected the ARC protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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