PTPRN Antibody (Center)

AMR09655G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMR09655G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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PTPRN Antibody (Center)

品牌	Leading Biology	貨號(hào)	AMR09655G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPRN antibody (Center).
分子量	105848 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	288-316 aa
靶點(diǎn)	This PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN.
亞型	Rabbit Ig
通用名	ICA3, ICA512
基因ID	5798
UniProt ID	Q16849
功能	Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
總結(jié)	The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and a single catalyticdomain, and thus represents a receptor-type PTP. This PTP was foundto be an autoantigen that is reactive with insulin-dependentdiabetes mellitus (IDDM) patient sera, and thus may be a potentialtarget of autoimmunity in diabetes mellitus.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
圖像	PTPRN Antibody (Center) (Cat. AMR09655G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PTPRN antibody detected the PTPRN protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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