品牌 |
Leading Biology | 貨號 |
APR17582G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NLE1 antibody (C-term).
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分子量 |
53320 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|Ref.5}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
343-372 aa
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靶點(diǎn) |
This NLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of human NLE1.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).
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總結(jié) |
NLE1 (Notchless protein homolog 1) contains 8 WD repeats and may be involved in the Notch signaling pathway.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Notchless protein homolog 1, NLE1
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圖像 |
NLE1 Antibody (C-term) (Cat. APR17582G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NLE1 antibody detected the NLE1 protein (arrow). |
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說明書 |
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數(shù)量 |
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