LOXL3 Antibody (C-term)

APR17208G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR17208G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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LOXL3 Antibody (C-term)

品牌	Leading Biology	貨號	APR17208G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LOXL3 antibody (C-term).
分子量	83166 Da
細(xì)胞定位	Antigen Cellular Localization: Isoform 1: Secreted, extracellular space
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	715-744 aa
靶點	This LOXL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 715-744 amino acids from the C-terminal region of human LOXL3.
亞型	Rabbit Ig
通用名	LOXL
基因ID	84695
UniProt ID	P58215
功能	Both isoforms function as amine oxidases toward elastin and different types of collagens. Isoform 1 shows the highest activity toward collagen type VIII, while Isoform 2 presents the highest activity toward collagen type IV.
總結(jié)	This gene encodes a member of the lysyl oxidase genefamily. The prototypic member of the family is essential to thebiogenesis of connective tissue, encoding an extracellularcopper-dependent amine oxidase that catalyses the first step in theformation of crosslinks in collagens and elastin. A highlyconserved amino acid sequence at the C-terminus end appears to besufficient for amine oxidase activity, suggesting that each familymember may retain this function. The N-terminus is poorly conservedand may impart additional roles in developmental regulation,senescence, tumor suppression, cell growth control, and chemotaxisto each member of the family. Alternatively spliced transcriptvariants of this gene have been reported but their full-lengthnature has not been determined.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:2000 IHC-P~~1:10~50
別名	Lysyl oxidase homolog 3, 143-, Lysyl oxidase-like protein 3, LOXL3, LOXL
圖像	All lanes : Anti-LOXL3 Antibody (C-term) at 1:2000 dilution Lane 1: human lung lysate Lane 2: human spleen lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Anti-LOXL3 Antibody (C-term) at 1:2000 dilution + human heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDa Blocking/Dilution buffer: 5% NFDM/TBST. LOXL3 Antibody (C-term) (Cat. APR17208G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LOXL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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