FGFRL1 Antibody (N-term)

APR15978G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR15978G		100 μl / ￥4950

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FGFRL1 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR15978G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FGFRL1 antibody (N-term).
分子量	54537 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	131-160 aa
靶點(diǎn)	This FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of human FGFRL1.
亞型	Rabbit Ig
通用名	FGFR5, FHFR
基因ID	53834
UniProt ID	Q8N441
功能	Has a negative effect on cell proliferation.
總結(jié)	The protein encoded by this gene is a member of thefibroblast growth factor receptor (FGFR) family, where amino acidsequence is highly conserved between members and throughoutevolution. FGFR family members differ from one another in theirligand affinities and tissue distribution. A full-lengthrepresentative protein would consist of an extracellular region,composed of three immunoglobulin-like domains, a single hydrophobicmembrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblastgrowth factors, setting in motion a cascade of downstream signals,ultimately influencing mitogenesis and differentiation. A markeddifference between this gene product and the other family membersis its lack of a cytoplasmic tyrosine kinase domain. The result isa transmembrane receptor that could interact with other familymembers and potentially inhibit signaling. Multiple alternativelyspliced transcript variants encoding the same isoform have beenfound for this gene.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P, WB, E
稀釋方法	IHC-P~~1:10~50 WB~~1:1000
別名	Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR
圖像	FGFRL1 Antibody (N-term) (Cat. APR15978G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGFRL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. FGFRL1 Antibody (N-term) (Cat. APR15978G) western blot analysis in A549,HepG2,Y79 cell line lysates (35ug/lane).This demonstrates the FGFRL1 antibody detected the FGFRL1 protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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