品牌 |
Leading Biology | 貨號 |
AMR09890G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SFTPC antibody (N-term).
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分子量 |
21053 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, surface film.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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免疫原 |
1-30 aa
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靶點 |
This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
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亞型 |
Rabbit Ig
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通用名 |
SFTP2
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基因ID |
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UniProt ID |
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功能 |
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces.
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總結 |
This gene encodes the pulmonary-associated surfactantprotein C (SPC), an extremely hydrophobic surfactant proteinessential for lung function and homeostasis after birth. Pulmonarysurfactant is a surface-active lipoprotein complex composed of 90%lipids and 10% proteins which include plasma proteins andapolipoproteins SPA, SPB, SPC and SPD. The surfactant is secretedby the alveolar cells of the lung and maintains the stability ofpulmonary tissue by reducing the surface tension of fluids thatcoat the lung. Multiple mutations in this gene have beenidentified, which cause pulmonary surfactant metabolism dysfunctiontype 2, also called pulmonary alveolar proteinosis due tosurfactant protein C deficiency, and are associated withinterstitial lung disease in older infants, children, and adults.Alternatively spliced transcript variants encoding differentprotein isoforms have been identified.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IF, E
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稀釋方法 |
WB~~1:1000
IF~~1:25
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別名 |
Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5, SFTPC, SFTP2
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圖像 |
All lanes : Anti-SFTPC Antibody (N-term) at 1:2000 dilution Lane 1: human lung lysates Lane 2: rat lung lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Immunofluorescent analysis of Human lung tissues, using SFTPC Antibody (N-term) (Cat. AMR09890G). AMR09890G was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). DAPI was used to stain the cell nuclear (blue). SFTPC Antibody (N-term) (Cat. AMR09890G) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SFTPC antibody detected the SFTPC protein (arrow). |
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說明書 |
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數(shù)量 |
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