SUV4-20H1 Antibody (C-term)

AMM08063G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM08063G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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SUV4-20H1 Antibody (C-term)

品牌	Leading Biology	貨號	AMM08063G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SUV4-20H1 antibody (C-term).
分子量	99187 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Chromosome. Note=Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	4-20 aa
靶點	This SUV4-20H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-789 amino acids from the C-terminal region of human SUV4-20H1.
亞型	Rabbit Ig
通用名	KMT5B
基因ID	51111
UniProt ID	Q4FZB7
功能	Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
總結(jié)	This gene encodes a protein that contains a SET domain.SET domains appear to be protein-protein interaction domains thatmediate interactions with a family of proteins that displaysimilarity with dual-specificity phosphatases (dsPTPases). Thefunction of this gene has not been determined. Two alternativelyspliced transcript variants have been found for this gene.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, FC, E
稀釋方法	WB~~1:1000 FC~~1:10~50
別名	Histone-lysine N-methyltransferase SUV420H1, Lysine N-methyltransferase 5B, Suppressor of variegation 4-20 homolog 1, Su(var)4-20 homolog 1, Suv4-20h1, SUV420H1, KMT5B
圖像	Western blot analysis of lysates from HT-29, PC-3 cell line (from left to right), using SUV4-20H1 Antibody (C-term)( AP12072B). AP12072B was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane. SUV4-20H1 Antibody (C-term) (Cat. AMM08063G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SUV4-20H1 antibody detected the SUV4-20H1 protein (arrow). SUV4-20H1 Antibody (C-term) (Cat. AMM08063G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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