品牌 |
Leading Biology | 貨號(hào) |
APR07642G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EDN1 antibody (C-term).
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分子量 |
24425 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
176-203 aa
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靶點(diǎn) |
This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Endothelins are endothelium-derived vasoconstrictor peptides.
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總結(jié) |
The protein encoded by this gene is proteolyticallyprocessed to release a secreted peptide termed endothelin 1. Thispeptide is a potent vasoconstrictor and is produced by vascularendothelial cells. Endothelin 1 also can affect the central nervoussystem. Two transcript variants encoding different isoforms havebeen found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, WB, IF, E
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稀釋方法 |
IHC-P~~1:50~100
WB~~1:1000
IF~~1:10~50
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別名 |
Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
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圖像 |
EDN1 Antibody (C-term) (Cat. APR07642G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EDN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. EDN1 Antibody (C-term) (Cat. APR07642G) western blot analysis in ZR-75-1,U251,MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the EDN1 antibody detected the EDN1 protein (arrow). Confocal immunofluorescent analysis of EDN1 Antibody (C-term)( APR07642G) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
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說(shuō)明書 |
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數(shù)量 |
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