PON1 Antibody (Center)

AMR09438G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMR09438G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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PON1 Antibody (Center)

品牌	Leading Biology	貨號	AMR09438G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PON1 antibody (Center).
分子量	39731 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted, extracellular space.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	118-145 aa
靶點(diǎn)	This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1.
亞型	Rabbit Ig
通用名	PON
基因ID	5444
UniProt ID	P27169
功能	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
總結(jié)	The enzyme encoded by this gene is an arylesterase thatmainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is anorganophosphorus anticholinesterase compound that is produced invivo by oxidation of the insecticide parathion. Polymorphisms inthis gene are a risk factor in coronary artery disease. The gene isfound in a cluster of three related paraoxonase genes at 7q21.3.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, FC, IHC-P, E
稀釋方法	WB~~1:1000 FC~~1:10~50 IHC-P~~1:10~50
別名	Serum paraoxonase/arylesterase 1, PON 1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
圖像	Western blot analysis of lysate from human blood plasma tissue lysate, using PON1 Antibody (Center)(Cat. AMR09438G). AMR09438G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. PON1 Antibody (Center) (Cat. AMR09438G) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. PON1 Antibody (Center) (Cat. AMR09438G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PON1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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