HLA-B Antibody (Center)

AMM05383G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM05383G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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HLA-B Antibody (Center)

品牌	Leading Biology	貨號	AMM05383G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HLA-B antibody (Center).
分子量	40460 Da
細胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	182-208 aa
靶點	This HLA-B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-208 amino acids from the Central region of human HLA-B.
亞型	Rabbit Ig
通用名	HLAB
基因ID	3106
UniProt ID	P01889
功能	Involved in the presentation of foreign antigens to the immune system.
總結(jié)	HLA-B belongs to the HLA class I heavy chain paralogues.This class I molecule is a heterodimer consisting of a heavy chainand a light chain (beta-2 microglobulin). The heavy chain isanchored in the membrane. Class I molecules play a central role inthe immune system by presenting peptides derived from theendoplasmic reticulum lumen. They are expressed in nearly allcells. The heavy chain is approximately 45 kDa and its genecontains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3encode the alpha1 and alpha2 domains, which both bind the peptide,exon 4 encodes the alpha3 domain, exon 5 encodes the transmembraneregion and exons 6 and 7 encode the cytoplasmic tail. Polymorphismswithin exon 2 and exon 3 are responsible for the peptide bindingspecificity of each class one molecule. Typing for thesepolymorphisms is routinely done for bone marrow and kidneytransplantation. Hundreds of HLA-B alleles have been described.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7, HLA-B, HLAB
圖像	HLA-B Antibody (Center) (Cat. AMM05383G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the HLA-B antibody detected the HLA-B protein (arrow).
說明書	Product Datasheet Protocol
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