CLDN7 Antibody (C-term)

APR15495G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15495G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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CLDN7 Antibody (C-term)

品牌	Leading Biology	貨號	APR15495G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN7 antibody (C-term).
分子量	22418 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Note=Co- localizes with EPCAM at the lateral cell membrane and tight junction
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	172-201 aa
靶點	This CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7.
亞型	Rabbit Ig
通用名	CEPTRL2, CPETRL2
基因ID	1366
UniProt ID	O95471
功能	Plays a major role in tight junction-specific obliteration of the intercellular space.
總結(jié)	This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions. Differential expression of this gene has beenobserved in different types of malignancies, including breastcancer, ovarian cancer, hepatocellular carcinomas, urinary tumors,prostate cancer, lung cancer, head and neck cancers, thyroidcarcinomas, etc.. Alternatively spliced transcript variantsencoding different isoforms have been found.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2
圖像	CLDN7 Antibody (C-term) (Cat. APR15495G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CLDN7 antibody detected the CLDN7 protein (arrow). CLDN7 antibody (C-term) (Cat. APR15495G) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLDN7 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. CLDN7 Antibody (C-term) (Cat. APR15495G) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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