THBS1 Antibody (N-term)

APR07044G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR07044G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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THBS1 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR07044G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality THBS1 antibody (N-term).
分子量	129383 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum. Sarcoplasmic reticulum
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	181-210 aa
靶點(diǎn)	This THBS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the N-terminal region of human THBS1.
亞型	Rabbit Ig
通用名	TSP, TSP1
基因ID	7057
UniProt ID	P07996
功能	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
總結(jié)	THBS1 is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50 FC~~1:10~50
別名	Thrombospondin-1, THBS1, TSP, TSP1
圖像	Western blot analysis of THBS1 Antibody (N-term) (Cat. APR07044G) in MDA-MB231 cell line lysates (35ug/lane). THBS1 (arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with THBS1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Confocal immunofluorescent analysis of THBS1 Antibody (N-term) ( APR07044G) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
說明書	Product Datasheet Protocol
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