DHH Antibody (Center)

AMM08615G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM08615G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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DHH Antibody (Center)

品牌	Leading Biology	貨號(hào)	AMM08615G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DHH antibody (Center).
分子量	43577 Da
細(xì)胞定位	Antigen Cellular Localization: Desert hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	195-223 aa
靶點(diǎn)	This DHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH.
亞型	Rabbit Ig
基因ID	50846
UniProt ID	O43323
功能	Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
總結(jié)	This gene encodes a member of the hedgehog family. Thehedgehog gene family encodes signaling molecules that play animportant role in regulating morphogenesis. This protein ispredicted to be made as a precursor that is autocatalyticallycleaved; the N-terminal portion is soluble and contains thesignalling activity while the C-terminal portion is involved inprecursor processing. More importantly, the C-terminal productcovalently attaches a cholesterol moiety to the N-terminal product,restricting the N-terminal product to the cell surface andpreventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadaldysgenesis (PGD) accompanied by minifascicular polyneuropathy. Thisprotein may be involved in both male gonadal differentiation andperineurial development.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Desert hedgehog protein, DHH, HHG-3, Desert hedgehog protein N-product, Desert hedgehog protein C-product, DHH
圖像	DHH Antibody (Center) (Cat. AMM08615G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the DHH antibody detected the DHH protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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