RHO Antibody (C-term)

APR14248G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14248G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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RHO Antibody (C-term)

品牌	Leading Biology	貨號	APR14248G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RHO antibody (C-term).
分子量	38893 Da
細胞定位	Antigen Cellular Localization: Membrane; Multi-pass membrane protein Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia
宿主	Rabbit
種屬反應性	Human, Mouse, Rat
免疫原	310-339 aa
靶點	This RHO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-339 amino acids from the C-terminal region of human RHO.
亞型	Rabbit Ig
通用名	OPN2
基因ID	6010
UniProt ID	P08100
功能	Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
總結(jié)	Retinitis pigmentosa is an inherited progressive diseasewhich is a major cause of blindness in western communities. It canbe inherited as an autosomal dominant, autosomal recessive, orX-linked recessive disorder. In the autosomal dominant form,whichcomprises about 25% of total cases, approximately 30% of familieshave mutations in the gene encoding the rod photoreceptor-specificprotein rhodopsin. This is the transmembrane protein which, whenphotoexcited, initiates the visual transduction cascade. Defects inthis gene are also one of the causes of congenital stationary nightblindness.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, E
稀釋方法	WB~~1:1000
別名	Rhodopsin, Opsin-2, RHO, OPN2
圖像	All lanes : Anti-RHO Antibody (C-term) at 1:2000 dilution Lane 1: mouse eyeball lysate Lane 2: rat eyeball lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST. RHO Antibody (C-term) (Cat. APR14248G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RHO antibody detected the RHO protein (arrow).
說明書	Product Datasheet Protocol
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