品牌 |
Leading Biology | 貨號(hào) |
AMM08611G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYTH4 antibody (C-term).
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分子量 |
45672 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
291-319 aa
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靶點(diǎn) |
This CYTH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human CYTH4.
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亞型 |
Rabbit Ig
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通用名 |
CYT4, PSCD4
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基因ID |
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UniProt ID |
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功能 |
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
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總結(jié) |
The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. The encoded protein exhibits GEP activity invitro with both ARF1 and ARF5 but is inactive with ARF6. Thestructures of this gene and CYTH1 are very similar. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Cytohesin-4, PH, SEC7 and coiled-coil domain-containing protein 4, CYTH4, CYT4, PSCD4
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圖像 |
CYTH4 Antibody (C-term) (Cat. AMM08611G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CYTH4 antibody detected the CYTH4 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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