全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR10917G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SECISBP2 antibody (Center).
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分子量 |
95462 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
501-530 aa
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靶點 |
This SECISBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-530 amino acids from the Central region of human SECISBP2.
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亞型 |
Rabbit Ig
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通用名 |
SBP2
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基因ID |
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UniProt ID |
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功能 |
Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
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總結(jié) |
The incorporation of selenocysteine into a proteinrequires the concerted action of an mRNA element called a secinsertion sequence (SECIS), a selenocysteine-specific translationelongation factor and a SECIS binding protein. With these elementsin place, a UGA codon can be decoded as selenocysteine. The genedescribed in this record encodes a nuclear protein that functionsas a SECIS binding protein. Mutations in this gene have beenassociated with a reduction in activity of a specific thyroxinedeiodinase, a selenocysteine-containing enzyme, and abnormalthyroid hormone metabolism.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Selenocysteine insertion sequence-binding protein 2, SECIS-binding protein 2, SECISBP2, SBP2
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圖像 |
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說明書 |
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數(shù)量 |
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