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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TSLP Antibody

TSLP Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR06432G 0.1 mg / ¥6950

TSLP Antibody

品牌

Leading Biology

貨號

APR06432G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TSLP Antibody.

分子量

Predicted: 17 kDa Observed: 23 kDa

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse

靶點(diǎn)

TSLP;

亞型

IgG

基因ID

UniProt ID

功能

Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

總結(jié)

TSLP Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. At least two differentially spliced isoforms of TSLP are known to exist.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

圖像

Western blot analysis of TSLP in A-20 cell lysate with TSLP antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.

Immunohistochemistry of TSLP in human brain tissue with TSLP antibody at 2.5 μg/mL.

Immunofluorescence of TSLP in Human Brain tissues with TSLP antibody at 20 μg/mL.

說明書

數(shù)量

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