We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality INSIG2 antibody - N-terminal region.
分子量
25kDa
細(xì)胞定位
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
宿主
Rabbit
種屬反應(yīng)性
Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog
Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
形式
Liquid
儲存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.