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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser43 Troponin I (cardiac) Antibody品牌 |
Leading Biology | 貨號 |
APR03404G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser43 Troponin I (cardiac) Antibody.
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分子量 |
25 KDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse, Rat
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靶點 |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser43 conjugated to KLH.
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基因ID |
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UniProt ID |
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總結(jié) |
Troponin I (TnI) is 1 of 3 subunits, along with troponin C (TnC) and Troponin T (TnT) of troponin complex found in cardiac (cTnI) and fast skeletal (fsTnI) muscle (Noland et al, 1995). Protein kinase C-mediated phosphorylation of cardiac myofilament proteins has been shown to depress the actomyosin interaction and may be important during heart failure. (Montgomery et al, 2002) Studies indicate that phosphorylation of Ser43 and Ser45 of cardiac troponin I plays a substantial role in the PKC-mediated depression. (Montgomery et al, 2002).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~ 1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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