品牌 |
Leading Biology |
貨號 |
APR02706G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TNIP3 Antibody (C-Terminus).
|
分子量 |
39kDa
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human, Mouse
|
靶點(diǎn) |
Human TNIP3
|
通用名 |
ABIN3, LIND
|
基因ID |
|
UniProt ID |
|
功能 |
Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
|
總結(jié) |
Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IHC-P, E
|
稀釋方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
|
圖像 |
Western blot of ABIN3 in human spleen tissue lysate with ABIN3 antibody at 1 ug/ml in (A) the...
Anti-TNIP3 antibody IHC of human adrenal.
|
說明書 |
|
數(shù)量 |
|