品牌 |
Leading Biology |
貨號 |
APG01094G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCR4 Antibody (Extracellular Domain).
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分子量 |
41kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Monkey
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靶點 |
Peptide sequence is <50% identical to other chemokine receptors in this region.
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通用名 |
CMKBR4
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基因ID |
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UniProt ID |
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功能 |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
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總結(jié) |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E, Flo
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稀釋方法 |
ELISA (1:30000), Flo (1:12), IHC-P (5 μg/ml), WB (1:500) ,
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圖像 |
Anti-CCR4 antibody IHC of human pancreas.
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說明書 |
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數(shù)量 |
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