品牌 |
Leading Biology |
貨號 |
APG01029G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TFAP2C / AP2 Gamma Antibody (C-Terminus).
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分子量 |
49kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Goat
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種屬反應性 |
Human, Rabbit, Monkey
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靶點 |
Human TFAP2C / AP2 Gamma.
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基因ID |
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UniProt ID |
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功能 |
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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總結(jié) |
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P, E
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稀釋方法 |
ELISA (1:128000), IHC-P (2.5 μg/ml),
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圖像 |
Anti-TFAP2C / AP2 Gamma antibody IHC of human skin.
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說明書 |
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數(shù)量 |
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